Oncology

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Cancer is a group of more than 200 diseases
                                                                        Äuncontrolled and unregulated growth of cells
Third leading cause of morbidity and mortality in the Philippines
Leading sites:
Lung,                                                             breast,         cervix,   liver,
colon,                                                            rectum,        prostate,
                                                                                                stomach
CANCER
Characterized by uncontrolled and unregulated growth of cells

TWO MAJOR DYSFUNCTIONS :
Defective cellular proliferation [growth]
Defective cellular differentiation
DEFECT IN CELLULAR PROLIFERATION
STEM CELLS
                                                                        Äpredetermined, undifferentiated cells
                                                                        Ädifferentiate and mature
                                                                        Äfunctioning cells of that tissue and only that tissue

CELL PROLIFERATION
                                                                        Äoriginates in the stem cell and begins when the stem cell enters the cell cycle
GENERATION TIME
                                                                        Ätime from when a cell enters the cell cycle to when the cell divides into two identical cells
MATURE CELLS
                                                                        Äcontinues to function until it degenerates and dies
cells of the body Äcontrolled by an intracellular mechanism that determines when cellular proliferation is necessary
Eg. Cellular proliferation equals cellular degeneration or death
NORMALLY
                                                                        cellular division and proliferation is activated only in the presence of cellular degeneration or death
                                                                        or if there is a physiologic need for more cells
Eg. Increase in WBC in the presence of infection
PHENOMENON OF PROLIFERATION CONTROL IN NORMAL CELLS
Contact inhibition
ÄNormal cells respect the boundaries and territory of the cells surrounding them
                                                                        Äneighboring cells inhibit cellular growth through physical contact of surrounding cell membranes
LOSS OF CONTACT INHIBITION IN CANCER
Äwill grow on top of one another and on top of or between normal cells
CANCER CELLS
Divide indiscriminately
Divide haphazardly
Produce more than two cells at the same time of mitosis
STEM CELL THEORY
The loss of intracellular control of proliferation results from a mutation of the stem cells
Stem cells are the target or origin of cancer development
DNA of the stem cell is substituted or rearranged
Stem cell is mutated
1-cell death due to damage from mutation or due to APOPTOSIS
                                                                        Êprogrammed cellular suicide
2-cell can recognize the damage and repair itself
3-mutated cell can survive and pass along the damage to daughter cells
Content
Title
Mutated cells that survive have the potential to become malignant
Eg. Cells with invasive and metastatic potential
PYRAMID EFFECT
                                                                        Äthere is continuous growth of tumor mass  1Ü2Ü4Ü8Ü16 and so on
DOUBLING TIME
                                                                        Äthe time required for a tumor mass to double in size
                                                                       
DEFECT IN CELLULAR DIFFERENTIATION
Orderly process that progresses from a state of immaturity to a state of maturity
Because all body cells are derived from the fertilized ova, all cells have the potential to perform all body function
As cells differentiate the potential to perform all body function is repressed
Mature cell is capable of performing only specific functions
DIFFERENTIATION OF HUMAN TISSUES

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One Response so far.

  1. Anneke Sergio says:
    July 16, 2019 at 7:42 PM

    HOW I GOT CURED OF HERPES VIRUS.

    Hello everyone out there, i am here to give my testimony about a herbalist called dr imoloa. i was infected with herpes simplex virus 2 in 2013, i went to many hospitals for cure but there was no solution, so i was thinking on how i can get a solution out so that my body can be okay. one day i was in the pool side browsing and thinking of where i can get a solution. i go through many website were i saw so many testimonies about dr imoloa on how he cured them. i did not believe but i decided to give him a try, i contacted him and he prepared the herpes for me which i received through DHL courier service. i took it for two weeks after then he instructed me to go for check up, after the test i was confirmed herpes negative. am so free and happy. so, if you have problem or you are infected with any disease kindly contact him on email drimolaherbalmademedicine@gmail.com. or / whatssapp --+2347081986098.
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