Malignant neoplasms originating in the bone marrow and lymphatic structures resulting in the proliferation of lymphocytes
Hodgkin’s lymphoma
Non-Hodgkin’s lymphoma
Hodgkin’s Lymphoma
Proliferation of abnormal giant, multinucleated cells (Reed-Sternberg cells) in the lymph nodes
Incidence: Bimodal age: 15 and above 50
Cause: unknown
Infection with Epstein-Barr Virus (EBV)
Genetic
Occupational toxins
Nursing Assessment:
Enlarged nodes (nontender, firm, movable), cervical region
B symptoms: fever, night sweats, Weight loss: worse prognosis
Malaise, pruritus
Hodgkin’s Lymphoma
Diagnosis:
Lymphangiogram
Staging via biopsy
Stage 1: single lymph node
Stage 11: 2 or more lymph nodes same side diaphragm
Stage 111: nodes both side diaphragm
Stage lV: metastasis other organs
Medical Management:
Radiation: Stage 1 and 11
Chemotherapy: Stage 111 and IV
Hodgkin’s Lymphoma
A-adriamycin
B – bleomycin
V-vinblastine
D-Dacarbazine
M- Nitrogen Mustard
O – oncovin
P – Procarbazine
P - Prednisone
Non-Hodgkin’s Lymphoma
Extranodal sites: GI tract, ovaries, testes, bones, CNS, liver, breast
Affect all ages
Significantly different from Hodgkin’s
Assessment:
Lymphadenopathy and B symptoms (fever, night sweats, weight loss)
Med Mx:
Chemotherapy:
Cyclophosphamide, adriamycin, oncovin, prednisone
Radiation
Categories:
Nursing Management,
Oncology